Effects of Testosterone and Estradiol Deficiency on Vasomotor Symptoms in Hypogonadal Men

Compounded percutaneous testosterone gel: use and effects in hypogonadal men.

BACKGROUND Current methods of testosterone replacement therapy are limited to fixed-dosage patches and depot injections. Neither of these methods provides ideal therapy because of the inflexibility of dosing and other nuisance problems associated with the patches and nonphysiologic hormone levels when depot injections are used. Testosterone gels offer the potential for convenience and ease of a...

Effect of testosterone replacement on trabecular architecture in hypogonadal men.

UNLABELLED We evaluated the effect of testosterone treatment on trabecular architecture by microMRI in 10 untreated severely hypogonadal men. After 2 years, microMRI parameters of trabecular connectivity improved significantly, suggesting the possibility that testosterone improves trabecular architecture. INTRODUCTION Osteoporosis, characterized by low BMD and diminished bone quality, is a si...

Symptoms of testosterone deficiency in early middle aged men.

UNLABELLED Symptoms of testosterone deficiency and concentrations of testosterone (T) and bioavailable testosterone (BT) were studied in 35- and 45-year-old men. METHODS A questionnaire, was sent to all 35- and 45-year-old men in Linköping, Sweden (n=1998). The questionnaire has earlier been used for 55- to 75-year-old men and included demographic data, medical history, different symptoms pos...

Effects of testosterone treatment on bone mineral density in hypogonadal men receiving intrathecal opioids.

BACKGROUND Opioid induced depression of sex hormones is a common finding in chronic pain patients receiving long-term opioids by oral, parenteral and even intrathecal routes of administration. The hypothalamic suppression by opioids leads to a hypogonadal state with low testosterone levels in males and subsequent low bone mineral density (BMD). METHODS We have studied the effects of intrathec...

Rosiglitazone increases testosterone in hypogonadal type 2 diabetic men.